Kinoshita Angela, Calcina Carmen Sandra Guzman, Sakamoto-Hojo Elza T, Camparato Marjori L, Picon Cesar, Baffa Oswaldo
Departamento de Física e Matemática, Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Av Bandeirantes 3900, 14040-901, Ribeirão Preto, SP, Brazil.
Health Phys. 2003 Apr;84(4):477-82. doi: 10.1097/00004032-200304000-00007.
Electron spin resonance and fluorescence in situ hybridization were used to evaluate the dose to the finger of a worker who accidentally touched a radiotherapy 60Co therapy source in November 1995. In September 1999, the middle finger was amputated. We estimated the dose to the bone of the finger to be 6.4 +/- 0.5 Gy using the electron spin resonance additive dose method and a corrected dose of about 20 +/- 3 Gy could be inferred by translocation analysis in peripheral lymphocytes using the fluorescence in situ hybridization method. This retrospective dosimetry was performed for the victim 4 y after the accident, but the compatibility of the results obtained by physical and biological methods reinforce their validity, although in the case of partial-body exposure the biological method has limitations and demonstrates the need to find appropriate correction factors.
1995年11月，一名工人意外接触到放射治疗用的60Co治疗源，利用电子自旋共振和荧光原位杂交技术评估了其手指所受剂量。1999年9月，该工人的中指被截肢。我们使用电子自旋共振累加剂量法估算该手指骨骼所受剂量为6.4±0.5 Gy，通过荧光原位杂交法对外周淋巴细胞进行易位分析推断出校正剂量约为20±3 Gy。此次回顾性剂量测定是在事故发生4年后对受害者进行的，尽管在局部身体照射的情况下生物方法存在局限性且表明需要找到合适的校正因子，但物理方法和生物方法所得结果的一致性增强了其有效性。
