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通过多位点序列分型鉴定在波兰分离出的多重耐药肺炎链球菌菌株。

Identification of multidrug-resistant Streptococcus pneumoniae strains isolated in Poland by multilocus sequence typing.

作者信息

Sadowy Ewa, Zhou Jiaji, Meats Emma, Gniadkowski Marek, Spratt Brian G, Hryniewicz Waleria

机构信息

Sera & Vaccines Central Research Laboratory, 00-725 Warsaw, Poland.

出版信息

Microb Drug Resist. 2003 Spring;9(1):81-6. doi: 10.1089/107662903764736373.

DOI:10.1089/107662903764736373
PMID:12705686
Abstract

Multilocus sequence typing (MLST) of 35 isolates of multidrug-resistant Streptococcus pneumoniae recovered in Poland during 1995-1996 distinguished 10 different sequence types (ST). The majority of the isolates were assigned to two Polish clones of serotypes 6B and 23F, although the international clones, Spain23F-1 and Spain9V-3, were also identified. Similar results were obtained using pulsed-field gel electrophoresis (PFGE), providing a direct comparison of these two typing methods.

摘要

对1995 - 1996年期间在波兰分离出的35株耐多药肺炎链球菌进行多位点序列分型(MLST),鉴别出10种不同的序列类型(ST)。尽管也鉴定出国际克隆株Spain23F - 1和Spain9V - 3,但大多数分离株被归为波兰的血清型6B和23F的两个克隆株。使用脉冲场凝胶电泳(PFGE)获得了相似结果,从而对这两种分型方法进行了直接比较。

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