来自球状球兰的环烯醚萜类化合物。

Iridoids from Globularia dumulosa.

作者信息

Kirmizibekmez Hasan, Akbay Pinar, Sticher Otto, Caliş Ihsan

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, TR-06100 Ankara, Turkey.

出版信息

Z Naturforsch C J Biosci. 2003 Mar-Apr;58(3-4):181-6. doi: 10.1515/znc-2003-3-407.

DOI:10.1515/znc-2003-3-407

PMID:12710725

Abstract

Two new iridoids, 10-O-benzoylglobularigenin (1) and dumuloside (2) were isolated from the aerial parts of Globularia dumulosa together with seven known iridoid glucosides, davisioside (3), aucubin (4), melampyroside (5), catalpol (6), 10-O-benzoylcatalpol (7), alpinoside (8) and deacetylalpinoside (9). Three phenylethanoid glycosides, verbascoside, decaffeoyl-verbascoside, leucosceptoside A and three flavone glucosides, pectolinarigenin 7-O-beta-D-glucopyranoside, nepetin 7-O-B-D-glucopyranoside, demethoxycentaureidin 7-O-beta-D-glucopyranoside were also isolated and characterized. The structure elucidation of the isolated compounds was performed by spectroscopic (UV, IR, HR-MALDIMS, 1D- and 2D NMR) methods.

摘要

从团花地杨梅的地上部分分离出两种新的环烯醚萜类化合物，10-O-苯甲酰基球花甙元（1）和团花甙（2），以及七种已知的环烯醚萜甙，即达维甙（3）、桃叶珊瑚甙（4）、黑麦草甙（5）、梓醇（6）、10-O-苯甲酰基梓醇（7）、高山甙（8）和去乙酰高山甙（9）。还分离并鉴定了三种苯乙醇甙，即毛蕊花甙、去咖啡酰毛蕊花甙、白花败酱甙A，以及三种黄酮甙，即橙皮素7-O-β-D-吡喃葡萄糖甙、荆芥甙7-O-β-D-吡喃葡萄糖甙、去甲氧基矢车菊素7-O-β-D-吡喃葡萄糖甙。通过光谱法（紫外、红外、高分辨基质辅助激光解吸电离质谱、一维和二维核磁共振）对分离得到的化合物进行结构解析。