Hsiung Stripp Diana C, Vaughn David, Van Arsdalen Keith, Whittington Richard
Department of Radiation Oncology, Hospital of the University of Pennsylvania, 2 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, U.S.A.
Am J Clin Oncol. 2003 Apr;26(2):197-9. doi: 10.1097/00000421-200304000-00020.
This is a report of three cases of classic seminoma in Down's syndrome patients treated at our institution. Review of literature shows an observation of increased occurrence of testicular cancer in patients with DS, however, with no definitive association documented. A brief discussion of the possible pathogenesis is presented.