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大鼠肥大细胞中磷脂和磷脂脂肪酸的组成

Composition of phospholipids and phospholipid fatty acids in rat mast cells.

作者信息

Strandberg K, Westerberg S

出版信息

Mol Cell Biochem. 1976 Apr 28;11(2):103-7. doi: 10.1007/BF01792791.

DOI:10.1007/BF01792791
PMID:1272255
Abstract

The composition of phospholipids and phospholipid fatty acids in isolated rat serous fluid mast cells was analyzed by thin layer chromatography, gas-liquid chromatography and mass spectrometry. The phospholipids constituted about 50% of the mast cell lipids and phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, phosphatidylcholine were identified. The phosphatidylethanolamine fraction contained aldehydes and the highest proportion of unsaturated fatty acids. Sphingomyelin contained predominantly saturated fatty acids whereas the ratio unsaturated fatty acids: saturated fatty acids for the other phospholipids was more close to 1.

摘要

采用薄层色谱法、气液色谱法和质谱法分析了分离出的大鼠浆膜肥大细胞中磷脂和磷脂脂肪酸的组成。磷脂约占肥大细胞脂质的50%,并鉴定出磷脂酰乙醇胺、磷脂酰丝氨酸、磷脂酰肌醇和磷脂酰胆碱。磷脂酰乙醇胺部分含有醛类和最高比例的不饱和脂肪酸。鞘磷脂主要含有饱和脂肪酸,而其他磷脂的不饱和脂肪酸与饱和脂肪酸的比例更接近1。

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