Drobniewski F, Strutt M, Smith G, Magee J, Flanagan P
PHLS Mycobacterium Reference Unit, South London Public Health Laboratory, Department of Infection Guy's, King's & St. Thomas' School of Medicine, Kings College Hospital (Dulwich), East Dulwich Grove, London SE22 8QF, UK.
Epidemiol Infect. 2003 Apr;130(2):235-7. doi: 10.1017/s0950268802008105.
This audit examines the ability of English and Welsh laboratories to diagnose Mycobacterium bovis infection. All 164 clinical laboratories submitting samples to the PHLS Mycobacterium Reference Unit and Regional Centres for Mycobacteriology were surveyed. Twenty per cent of responding centres did not use a pyruvate-containing medium or incubate for the minimum recommended period of 8 weeks. This study demonstrates the potential for the underdiagnosis of M. bovis infection in England and Wales. Possible reasons for underdiagnosis are discussed together with strategies to optimize recovery of M. bovis.
本次审计考察了英格兰和威尔士各实验室诊断牛分枝杆菌感染的能力。我们对向公共卫生实验室服务处分枝杆菌参考单位和分枝杆菌病区域中心提交样本的所有164家临床实验室进行了调查。20%的回复中心未使用含丙酮酸的培养基，或培养时间未达到建议的最短8周时间。本研究表明，在英格兰和威尔士，牛分枝杆菌感染可能存在诊断不足的情况。文中讨论了诊断不足的可能原因以及优化牛分枝杆菌检出率的策略。
