Scaife Courtney L, Curley Steven A
Department of Surgical Oncology, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 444, Houston, TX 77030, USA.
Surg Oncol Clin N Am. 2003 Jan;12(1):243-55. doi: 10.1016/s1055-3207(02)00088-1.
RFA is a technology that can be applied to unresectable hepatic malignancies without significant morbidity when patients and treatment approach are chosen carefully. The results of therapy provide patients with an improved chance for survival despite their unresectable disease. There are limitations of imaging to monitor treatment and treatment response. At this point, an intraoperative technique has greater treatment success than a percutaneous technique and this is likely associated with periprocedural imaging limitations with a percutaneous technique and the ability to more easily perform inflow vascular occlusion with an intraoperative approach. RFA is a potentially effective local tumor therapy for unresectable hepatic malignancies. Improved technology and concurrent application of RFA with other treatment modalities should continue to improve tumor response and patient survival for patients with unresectable hepatic malignancies.
射频消融术（RFA）是一项技术，若能谨慎选择患者和治疗方法，它可应用于无法切除的肝脏恶性肿瘤，且不会引发明显的并发症。尽管患者的疾病无法切除，但治疗结果为患者提供了更高的生存几率。在监测治疗及治疗反应方面，影像学存在局限性。目前，术中技术比经皮技术具有更高的治疗成功率，这可能与经皮技术在围手术期的影像学局限性以及术中方法更易于进行流入血管闭塞有关。对于无法切除的肝脏恶性肿瘤，射频消融术是一种潜在有效的局部肿瘤治疗方法。技术的改进以及射频消融术与其他治疗方式的联合应用应会持续改善无法切除肝脏恶性肿瘤患者的肿瘤反应和生存情况。
