Flytström Ingela, Bergbrant Ing-Marie, Bråred Johanna, Brandberg Lena Lind
Department of Dermatology and Venereology, Sahlgrenska University Hospital, Göteborg, Sweden.
Acta Derm Venereol. 2003;83(2):121-3. doi: 10.1080/00015550310007463.
Infection can be a trigger and an aggravating factor in psoriasis. Antibacterial and/or antifungal agents are commonly used in the treatment of intertriginous psoriasis, because it is believed that flexures in psoriasis are often colonized by Candida species and Staphylococcus aureus. Bacterial and fungal cultures were studied from 32 psoriatic patients with no topical treatment in the intertriginous areas, from 13 psoriatic patients treated with topical steroids and from 19 patients with no psoriasis or other affections of the skinfolds. Untreated psoriatic patients were colonized by S. aureus significantly more often than the control group but infection seemed to be unlikely. Candida was not found in any of the groups. It is proposed that intertriginous psoriasis be treated with topical steroids alone and that the routine use of antimycotic and antibacterial combinations should be avoided.
感染可能是银屑病的一个触发因素和加重因素。抗菌和/或抗真菌药物常用于治疗间擦部位银屑病，因为人们认为银屑病的褶皱部位常被念珠菌属和金黄色葡萄球菌定植。对32例间擦部位未进行局部治疗的银屑病患者、13例接受局部类固醇治疗的银屑病患者以及19例无银屑病或其他皮肤褶皱病变的患者进行了细菌和真菌培养研究。未经治疗的银屑病患者被金黄色葡萄球菌定植的频率明显高于对照组，但感染似乎不太可能发生。在所有组中均未发现念珠菌。建议间擦部位银屑病仅用局部类固醇治疗，应避免常规使用抗真菌和抗菌联合用药。
