Manguro Lawrence Onyango Arot, Ugi Ivar, Lemmen Peter
Chemistry Department, University of Nairobi, Kenya.
Chem Pharm Bull (Tokyo). 2003 May;51(5):483-6. doi: 10.1248/cpb.51.483.
Fractionation of a steam distilled residue of Commiphora confusa resin has yielded four novel dammarane triterpenes characterised as (20S)-3beta-acetoxy-12beta,16beta-trihydroxydammar-24-ene, (20S)-12beta,16beta-trihydroxydammar-24-ene-3beta-O-beta-glucopyranoside, (20S)-3beta-acetoxy-12beta,16beta,25-tetrahydroxydammar-23-ene, and (20S)-3beta,12beta,16beta,25-pentahydroxydammar-23-ene. The known compounds beta-amyrin, 3beta-amyrinacetate, 2-methoxyfuranodienone, 2-acetoxyfuranodienone, (20R)-3beta-acetoxy-16beta-dihydroxydammar-24-ene, (20R)-3beta,16beta-trihydroxydammar-24-ene, 3beta-acetoxy-16beta-hydroxydammar-24-ene, 3beta-hydroxydammar-24-ene, 3beta-acetoxydammar-24-ene, and beta-sistosterol were also isolated from the same extract. The structures of the compounds were determined using spectroscopic, physical, and chemical methods.
对索马里没药树脂的水蒸气蒸馏残渣进行分馏，得到了四种新型达玛烷三萜，分别为(20S)-3β-乙酰氧基-12β,16β-三羟基达玛-24-烯、(20S)-12β,16β-三羟基达玛-24-烯-3β-O-β-葡萄糖吡喃糖苷、(20S)-3β-乙酰氧基-12β,16β,25-四羟基达玛-23-烯和(20S)-3β,12β,16β,25-五羟基达玛-23-烯。还从同一提取物中分离出了已知化合物β-香树脂醇、3β-香树脂醇乙酸酯、2-甲氧基呋喃二烯酮、2-乙酰氧基呋喃二烯酮、(20R)-3β-乙酰氧基-16β-羟基达玛-24-烯、(20R)-3β,16β-三羟基达玛-24-烯、3β-乙酰氧基-16β-羟基达玛-24-烯、3β-羟基达玛-24-烯、3β-乙酰氧基达玛-24-烯和β-谷甾醇。通过光谱、物理和化学方法确定了这些化合物的结构。
