Weakley David R, Birch Eileen, McClatchey Scott K, Felius Joost, Parks Marshall M, Stager David
Department of Ophthalmology, The University of Texas Southwestern Medical Center of Dallas, Dallas, TX, USA.
J AAPOS. 2003 Apr;7(2):86-90. doi: 10.1016/mpa.2003.S1091853103000090.
The advent of intraocular lens implantation after pediatric cataract surgery necessitates an increased understanding of refractive development. The significant variation in rate and amount of refractive change among eyes, both aphakic and pseudophakic, is well recognized, although the causes of such variation remain unclear. The purpose of this study was to determine if a correlation exists between the rate of refractive growth (RRG) and visual acuity outcome in pediatric aphakia.
Multicenter, retrospective observational case series. One hundred and twenty-five eyes of 85 patients with cataract surgery before 1 year of age and a minimum of 3 years of follow-up were analyzed. RRG was calculated for each eye using the logarithmic model of ocular growth and compared with final logMAR acuity using linear regression.
The correlation of RRG with final logMAR acuity was statistically significant (r(2) = 0.10; P <.01), ie, 10% of variance in RRG is related to acuity outcome. The correlation was higher in unilaterally aphakic patients (n = 44; r(2) = 0.19; P <.01) than in bilaterally aphakic patients (n = 81; r(2) = 0.08; P <.01). Eyes with visual acuity of 20/60 or better had a significantly lower RRG than those with poorer acuity (4.1 v 5.4 diopters (D); P <.01).
RRG in aphakia is correlated with visual acuity outcome. Eyes with poorer acuity have a greater RRG.
小儿白内障手术后人工晶状体植入的出现，使得有必要加深对屈光发育的理解。无晶状体眼和人工晶状体眼之间屈光变化的速率和量存在显著差异，这一点已得到充分认识，尽管这种差异的原因仍不清楚。本研究的目的是确定小儿无晶状体眼中屈光增长速率（RRG）与视力结果之间是否存在相关性。
多中心回顾性观察病例系列。分析了85例1岁前接受白内障手术且至少随访3年的患者的125只眼。使用眼生长的对数模型计算每只眼的RRG，并通过线性回归将其与最终的logMAR视力进行比较。
RRG与最终logMAR视力的相关性具有统计学意义（r² = 0.10；P <.01），即RRG中10%的变异与视力结果相关。单侧无晶状体患者（n = 44；r² = 0.19；P <.01）的相关性高于双侧无晶状体患者（n = 81；r² = 0.08；P <.01）。视力为20/60或更好的眼的RRG显著低于视力较差的眼（4.1对5.4屈光度（D）；P <.01）。
无晶状体眼中的RRG与视力结果相关。视力较差的眼的RRG更大。
