Rau Harald, Bührer Michael, Weitkunat Rolf
Department of Psychiatry, Hospital Gilead, Bethel, Remterweg 69/71, D 33617 Bielefeld, Germany.
Appl Psychophysiol Biofeedback. 2003 Mar;28(1):37-46. doi: 10.1023/a:1022352631988.
We investigated whether biofeedback of the R-wave-to-pulse interval, a measure related to the pulse wave velocity, enables participants with either high or low arterial blood pressure to modify their blood pressure. Twelve participants with high blood pressure (mean systolic blood pressure = 142.6 +/- 13.5 mmHg; mean diastolic blood pressure = 99.9 +/- 12.3 mmHg) and 10 participants with low blood pressure (mean systolic blood pressure = 104.8 +/- 6.6 mmHg; mean diastolic blood pressure = 73.2 +/- 4.2 mmHg) received 3 individual sessions of RPI biofeedback within a 2-week period. Participants with high blood pressure were rewarded for decreasing and participants with low blood pressure for increasing their blood pressure. Standard arm-cuff blood pressure measurements across the sessions served as dependent variables. Participants with high blood pressure achieved significant reductions of systolic (15.3 mmHg) and diastolic (17.8 mmHg) blood pressure levels from the beginning of the first to the end of the last training session. In contrast, participants with low blood pressure achieved significant increases in systolic (12.3 mmHg) and diastolic (8.4 mmHg) blood pressure levels. The degree of blood pressure changes in this study might be of clinical relevance. With prolonged and refined training regimens, even larger effects seem to be likely.
我们研究了与脉搏波速度相关的R波至脉搏间期生物反馈是否能使动脉血压高或低的参与者调节其血压。12名高血压参与者（平均收缩压 = 142.6 +/- 13.5 mmHg；平均舒张压 = 99.9 +/- 12.3 mmHg）和10名低血压参与者（平均收缩压 = 104.8 +/- 6.6 mmHg；平均舒张压 = 73.2 +/- 4.2 mmHg）在2周内接受了3次单独的RPI生物反馈训练。高血压参与者因血压降低而获得奖励，低血压参与者因血压升高而获得奖励。各训练时段的标准袖带血压测量值作为因变量。高血压参与者从第一次训练开始到最后一次训练结束时，收缩压（15.3 mmHg）和舒张压（17.8 mmHg）水平显著降低。相比之下，低血压参与者的收缩压（12.3 mmHg）和舒张压（8.4 mmHg）水平显著升高。本研究中血压变化的程度可能具有临床意义。通过长期和精细的训练方案，似乎可能会产生更大的效果。
