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在疾病程度有限的地区消除沙眼。

Eliminating trachoma in areas with limited disease.

作者信息

Gaynor Bruce D, Miao Yinghui, Cevallos Vicky, Jha Hem, Chaudary J S P, Bhatta Ramesh, Osaki-Holm Susan, Yi Elizabeth, Schachter Julius, Whitcher John P, Lietman Thomas

机构信息

WHO Collaborating Center, F.I. Proctor Foundation, Department of Ophthalmology, University of California-San Francisco, San Francisco, CA 94143, USA.

出版信息

Emerg Infect Dis. 2003 May;9(5):596-8. doi: 10.3201/eid0905.020577.

DOI:10.3201/eid0905.020577
PMID:12737745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2972764/
Abstract

The common wisdom is that a trachoma program cannot eliminate ocular chlamydia from a community, just reduce infection to a level where blindness would be minimal. We describe the success of multiple mass antibiotic treatments, demonstrating that complete elimination of infection may be an attainable goal in an area with modest disease.

摘要

普遍的观点认为,沙眼防治项目无法从社区中消除眼部衣原体感染,只能将感染率降低到致盲风险最小的水平。我们描述了多次大规模抗生素治疗的成功案例,证明在疾病程度较轻的地区,完全消除感染可能是一个可以实现的目标。

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1
Eliminating trachoma in areas with limited disease.在疾病程度有限的地区消除沙眼。
Emerg Infect Dis. 2003 May;9(5):596-8. doi: 10.3201/eid0905.020577.
2
Impact of a single round of mass drug administration with azithromycin on active trachoma and ocular Chlamydia trachomatis prevalence and circulating strains in The Gambia and Senegal.单次阿奇霉素群体药物治疗对冈比亚和塞内加尔活动性沙眼和眼衣原体流行率及循环株的影响。
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Adverse and beneficial secondary effects of mass treatment with azithromycin to eliminate blindness due to trachoma in Nepal.阿奇霉素群体给药消除尼泊尔沙眼致盲的不良和有益副作用
Clin Infect Dis. 2002 Aug 15;35(4):395-402. doi: 10.1086/341414. Epub 2002 Jul 23.
5
A rationale for continuing mass antibiotic distributions for trachoma.持续进行大规模抗生素分配以治疗沙眼的理论依据。
BMC Infect Dis. 2007 Aug 7;7:91. doi: 10.1186/1471-2334-7-91.
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Trachoma in 3 Amerindian Communities, Venezuelan Amazon, 2018.

本文引用的文献

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Rationale for mass antibiotic distribution for trachoma elimination.用于消除沙眼的大规模抗生素分发的基本原理。
Int Ophthalmol Clin. 2002 Winter;42(1):85-92. doi: 10.1097/00004397-200201000-00012.
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Does clinical diagnosis indicate ocular chlamydial infection in areas with a low prevalence of trachoma?在沙眼低流行地区,临床诊断能否提示眼部衣原体感染?
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Mass azithromycin distribution for hyperendemic trachoma following a cluster-randomized trial: A continuation study of randomly reassigned subclusters (TANA II).大规模阿奇霉素分发用于流行地区沙眼的随机对照试验后:重新随机分组的亚组的延续研究(TANA II)。
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Ocular Chlamydia trachomatis Infection Under the Surgery, Antibiotics, Facial Cleanliness, and Environmental Improvement Strategy in Amhara, Ethiopia, 2011-2015.2011-2015 年埃塞俄比亚阿姆哈拉地区手术、抗生素、面部清洁和环境改善策略下的沙眼衣原体眼部感染
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The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve trachoma-endemic island communities in West Africa.单次社区群体阿奇霉素治疗对西非未经治疗的沙眼流行岛屿社区疾病严重程度和眼部沙眼衣原体负荷的影响。
Parasit Vectors. 2017 Dec 28;10(1):624. doi: 10.1186/s13071-017-2566-x.
7
Mass drug administration: the importance of synchrony.群体药物管理:同步性的重要性。
Math Med Biol. 2017 Jun 1;34(2):241-260. doi: 10.1093/imammb/dqw005.
8
Control of Trachoma from Achham District, Nepal: A Cross-Sectional Study from the Nepal National Trachoma Program.尼泊尔阿查姆地区沙眼防治:来自尼泊尔国家沙眼项目的横断面研究
PLoS Negl Trop Dis. 2016 Feb 12;10(2):e0004462. doi: 10.1371/journal.pntd.0004462. eCollection 2016 Feb.
9
The distribution of the prevalence of ocular chlamydial infection in communities where trachoma is disappearing.沙眼正在消失的社区中眼部衣原体感染患病率的分布情况。
Epidemics. 2015 Jun;11:85-91. doi: 10.1016/j.epidem.2015.03.003. Epub 2015 Mar 21.
10
The distribution of ocular Chlamydia prevalence across Tanzanian communities where trachoma is declining.在沙眼发病率正在下降的坦桑尼亚各社区中眼部衣原体感染率的分布情况。
PLoS Negl Trop Dis. 2015 Mar 27;9(3):e0003682. doi: 10.1371/journal.pntd.0003682. eCollection 2015 Mar.
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Clinically active trachoma versus actual Chlamydial infection.临床活动性沙眼与实际衣原体感染
Med J Aust. 2000 Jan 17;172(2):93-4. doi: 10.5694/j.1326-5377.2000.tb139214.x.
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Azithromycin in control of trachoma.阿奇霉素用于控制沙眼
Lancet. 1999 Aug 21;354(9179):630-5. doi: 10.1016/S0140-6736(98)12387-5.
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Reliability of clinical diagnosis in identifying infectious trachoma in a low-prevalence area of Nepal.尼泊尔低流行地区临床诊断沙眼感染的可靠性。
Bull World Health Organ. 1999;77(6):461-6.
7
Global elimination of trachoma: how frequently should we administer mass chemotherapy?全球消除沙眼:我们应多久进行一次大规模化疗?
Nat Med. 1999 May;5(5):572-6. doi: 10.1038/8451.
8
Conference synthesis and vision for the future.会议总结与未来展望。
Bull World Health Organ. 1998;76 Suppl 2(Suppl 2):109-12.
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Report of the Workgroup on Bacterial Diseases.细菌性疾病工作组报告
Bull World Health Organ. 1998;76 Suppl 2(Suppl 2):85-8; discussion 104-8.
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The principles of disease elimination and eradication.疾病消除和根除的原则。
Bull World Health Organ. 1998;76 Suppl 2(Suppl 2):22-5.