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伴有恶性征象的巨大肺内孤立性纤维瘤。

Giant intrapulmonary solitary fibrous tumor with signs of malignancy.

作者信息

Marcinkevičiūtė Kristina, Jagelavičius Žymantas, Žurauskas Edvardas, Janilionis Ričardas

机构信息

Faculty of Medicine, Vilnius University, Vilnius LT-03101, Lithuania.

Department of Thoracic Surgery, Center of Cardio-Thoracic Surgery, Clinic of Chest Diseases, Immunology and Allergology, Institute of Clinical Medicine, Faculty of Medicine, Vilnius University, Vilnius LT-08661, Lithuania.

出版信息

J Surg Case Rep. 2024 Jan 16;2024(1):rjad741. doi: 10.1093/jscr/rjad741. eCollection 2024 Jan.

Abstract

Solitary fibrous tumor (SFT) is an extremely rare mesenchymal neoplasm usually detected in the pleura, which generally follows a benign course. The localization inside lung parenchyma has more rarely been reported. We present a case of a 51-year-old male with a dry cough, dyspnea, chest pain, and increased perspiration. Radiological images revealed a giant circumscribed mass on the right side of the chest. A transbronchial cryobiopsy of the lung was performed and revealed an SFT. The right upper lobectomy through lateral thoracotomy was performed. The pathological examination confirmed an SFT with a central zone of necrosis that is a sign of malignancy. At a 2-year follow-up, the patient is free of symptoms and with no evidence of recurrence. Although the intrapulmonary localization of an SFT is a rare entity, we should be aware of it as a potential malignant pulmonary neoplasm.

摘要

孤立性纤维瘤(SFT)是一种极为罕见的间叶性肿瘤,通常在胸膜中发现,一般病程呈良性。肺实质内的定位情况较少被报道。我们报告一例51岁男性患者,有干咳、呼吸困难、胸痛和多汗症状。影像学检查显示右侧胸部有一个巨大的边界清晰的肿块。对肺部进行了经支气管冷冻活检,结果显示为SFT。通过侧胸壁切口进行了右上肺叶切除术。病理检查证实为SFT,伴有中央坏死区,这是恶性的迹象。在2年的随访中,患者无症状,无复发迹象。尽管SFT在肺内定位是一种罕见情况,但我们应将其视为一种潜在的恶性肺肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8beb/10795905/fad0e36f9958/rjad741f1.jpg

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