神经生物学建模的通用框架：在前庭系统中的应用。
A general framework for neurobiological modeling: an application to the vestibular system.
作者信息
Eliasmith Chris, Westover M B, Anderson C H
机构信息
Department of Philosophy, Department of Systems Design Engineering, University of Waterloo, Waterloo, Ont., Canada.
出版信息
Neurocomputing (Amst). 2002 Jun;44-46:1071-6. doi: 10.1016/s0925-2312(02)00418-6.
The otolith organs in the vestibular system are excellent detectors of linear accelerations. However, any measurement of linear acceleration is ambiguous between a tilt in a gravitational field and an inertial acceleration. Angelaki et al. have put forward a general hypothesis about how inertial accelerations can be computed based on vestibular signals (J. Neurosci. 19 (1999) 316). We have constructed a realistic, detailed model of the relevant systems to test this hypothesis. The model produces useful predictions about what kinds of neurons should be found in the vestibular nucleus if such a computation is actually performed in the vestibular system. The model is constructed using general principles of neurobiological simulation (J. Neurophys. 84 (2000) 2113).
前庭系统中的耳石器官是线性加速度的优秀探测器。然而，线性加速度的任何测量在重力场中的倾斜和惯性加速度之间都是模糊的。安杰拉基等人提出了一个关于如何根据前庭信号计算惯性加速度的一般假设（《神经科学杂志》19卷（1999年）316页）。我们构建了相关系统的逼真、详细模型来检验这一假设。如果这种计算确实在前庭系统中进行，该模型对前庭核中应该发现何种类型的神经元产生了有用的预测。该模型是使用神经生物学模拟的一般原理构建的（《神经生理学杂志》84卷（2000年）2113页）。
Zotero 插件