在三种不同环境下对老年受试者进行五项老年抑郁量表的验证。
Validation of the five-item geriatric depression scale in elderly subjects in three different settings.
作者信息
Rinaldi Patrizia, Mecocci Patrizia, Benedetti Claudia, Ercolani Sara, Bregnocchi Mario, Menculini Giuseppe, Catani Marco, Senin Umberto, Cherubini Antonio
机构信息
Institute of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia Medical School, Italy.
出版信息
J Am Geriatr Soc. 2003 May;51(5):694-8. doi: 10.1034/j.1600-0579.2003.00216.x.
OBJECTIVES
To test the effectiveness of a five-item version of the Geriatric Depression Scale (GDS) for the screening of depression in community-dwelling older subjects, hospitalized older patients, and nursing home residents.
DESIGN
A cross-sectional study.
SETTING
A geriatric acute care ward, a geriatric outpatient clinic, and a nursing home.
PARTICIPANTS
One hundred eighty-one cognitively intact older subjects.
MEASUREMENT
All the participants had a comprehensive geriatric assessment including a neuropsychological evaluation by a geriatrician experienced in the management of depression. The five-item GDS was compared with the 15-item version of the GDS using the clinical diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria as the criterion standard. The sensitivity, the specificity, the overall accuracy, positive and negative predictive values, and positive and negative likelihood ratios were calculated. The agreement between each of two different versions of the GDS and the clinical diagnosis and the test-retest and the interrater reliability of the five-item scale were also evaluated.
RESULTS
In the whole sample, 48.1% of the subjects were depressed. The five-item GDS had a sensitivity of 0.94 (0.91-0.98), a specificity of 0.81 (0.75-0.87), a positive predictive value of 0.81 (0.75-0.87), a negative predictive value of 0.94 (0.90-0.97), a positive likelihood ratio of 4.92 (4.39-5.5), and a negative likelihood ratio of 0.07 (0.06-0.08). The five-item GDS and the 15-item GDS showed a significant agreement with the clinical diagnosis of depression (kappa = 0.74 for both scales). The five-item GDS had good interrater reliability (kappa = 0.88) and test-retest reliability (kappa = 0.84). Similar values were obtained in each setting and in both sexes.
CONCLUSION
The five-item GDS is as effective as the 15-item GDS for the screening of depression in cognitively intact older subjects.
目的
测试老年抑郁量表(GDS)的五项版本对社区居住的老年受试者、住院老年患者和养老院居民进行抑郁筛查的有效性。
设计
一项横断面研究。
地点
老年急性护理病房、老年门诊诊所和一家养老院。
参与者
181名认知功能完好的老年受试者。
测量
所有参与者均接受了全面的老年评估,包括由一位在抑郁症管理方面经验丰富的老年病专家进行的神经心理学评估。以《精神疾病诊断与统计手册》第四版标准的临床诊断作为标准,将GDS的五项版本与15项版本进行比较。计算敏感性、特异性、总体准确性、阳性和阴性预测值以及阳性和阴性似然比。还评估了两个不同版本的GDS与临床诊断之间的一致性以及五项量表的重测信度和评分者间信度。
结果
在整个样本中,48.1%的受试者患有抑郁症。GDS的五项版本敏感性为0.94(0.91 - 0.98),特异性为0.81(0.75 - 0.87),阳性预测值为0.81(0.75 - 0.87),阴性预测值为0.94(0.90 - 0.97),阳性似然比为4.92(4.39 - 5.5),阴性似然比为0.07(0.06 - 0.08)。GDS的五项版本和15项版本与抑郁症的临床诊断显示出显著一致性(两个量表的kappa值均为0.74)。GDS的五项版本具有良好的评分者间信度(kappa = 0.88)和重测信度(kappa = 0.84)。在每个地点和男女两性中均获得了类似的值。
结论
对于认知功能完好的老年受试者,GDS的五项版本在抑郁筛查方面与15项版本同样有效。