Sazonov V F
Antibiotiki. 1976 Apr;21(4):350-2.
The dynamics of penicillin concentrations in the blood and lung tissue of animals with chronic experimental pneumonia after its repeated administration in combination with prednisolone was studied. An increase in the period, during which the antibiotic was found in the lung tissue of the animals under conditions of its repeated use with prednisolone was shown.
研究了在慢性实验性肺炎动物中,青霉素与泼尼松龙联合重复给药后血液和肺组织中青霉素浓度的动态变化。结果显示,在青霉素与泼尼松龙重复使用的情况下,动物肺组织中发现抗生素的时间有所延长。