Bobrov V I, Beletskaia G T
Antibiotiki. 1984 Dec;29(12):913-6.
The use of benzylpenicillin and ampicillin in combination with sulfalen or sulfadimethoxine increased the levels of the penicillins and sulfalen in some organs and tissues of rats. This was accompanied by a rise in the concentration gradients of the drugs. It is concluded that the combined use of the penicillins and sulfanilamides determines their increased penetration from the blood into other organs and tissues of the host.
将苄青霉素和氨苄青霉素与磺胺林或磺胺二甲氧嘧啶联合使用，可提高大鼠某些器官和组织中青霉素和磺胺林的水平。这伴随着药物浓度梯度的升高。得出的结论是，青霉素和磺胺类药物的联合使用决定了它们从血液到宿主其他器官和组织的渗透增加。
