Evans W O, Robinson S M, Horstman D H, Jackson R E, Weiskopf R B
Aviat Space Environ Med. 1976 May;47(5):512-6.
Treatment by 4 d of residence at 1600 m plus the administration of 500 mg acetazolamide b.i.d. for the last 2 d at 1600 m and the first 2 d at 4300 m was compared with no treatment prior to ascent to 4300 m for prophylaxis of acute mountain sickness. The treatment successfully prevented almost all symptoms of acute mountain sickness. It had no effect on the diminished capacity for maximal or prolonged heavy physical work. The treatment produced a relative acidosis and a comparatively greater arterial oxygen tension at 4300 m.
将在1600米处居住4天，加上在1600米处最后2天以及在4300米处最初2天每天两次服用500毫克乙酰唑胺的治疗方法，与在上升到4300米之前不进行任何治疗以预防急性高原病的方法进行了比较。该治疗成功预防了几乎所有急性高原病症状。它对最大或长时间重体力劳动能力的下降没有影响。该治疗在4300米处产生了相对酸中毒和相对较高的动脉血氧张力。
