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对一起与英格兰萨默塞特郡学童前往法国旅行相关的大肠杆菌O157感染疫情的调查。

Investigation of an outbreak of E. coli O157 infections associated with a trip to France of schoolchildren from Somerset, England.

作者信息

Duffell E, Espié E, Nichols T, Adak G K, De Valk H, Anderson K, Stuart J M

机构信息

Communicable Diseases Surveillance Centre (South West), Public Health Laboratory, Gloucestershire Royal Hospital, Gloucester, England, United Kingdom.

出版信息

Euro Surveill. 2003 Apr;8(4):81-6. doi: 10.2807/esm.08.04.00406-en.

DOI:10.2807/esm.08.04.00406-en
PMID:12764237
Abstract

A retrospective cohort study was conducted after 2 confirmed and 8 probable cases of VTEC 0157 occurred in a schoolgroup from Somerset following a trip to France. The strain of the 2 confirmed cases was vero-cytotoxin type 2, phage type 34. Despite its low statistical power due to small numbers, this study suggested the most likely vehicle of infection was cucumber salad (crude RR=4.3, 95%CI [0.6-29], adjusted OR=107, 95%CI indeterminate, p=0.08). The cucumbers were purchased from Belgium but it was not possible to trace them back to source. The international nature of this outbreak emphasises the importance of close collaboration between organisations in the management of outbreaks, of ensuring international standards in food safety, and of agreeing a common standard in VTEC typing across Europe.

摘要

在一个来自萨默塞特郡的学校团体前往法国旅行后,出现了2例确诊和8例可能的VTEC 0157病例,之后开展了一项回顾性队列研究。2例确诊病例的菌株为2型志贺毒素、34型噬菌体。尽管由于样本量小导致统计效力较低,但该研究表明,最有可能的感染载体是黄瓜沙拉(粗相对危险度=4.3,95%置信区间[0.6-29],调整后的比值比=107,95%置信区间无法确定,p=0.08)。这些黄瓜购自比利时,但无法追溯其来源。此次疫情的国际性凸显了各组织在疫情管理中密切合作、确保食品安全国际标准以及商定欧洲通用的VTEC分型标准的重要性。

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