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[前列腺癌与急性弥散性血管内凝血。基于三例病例的治疗管理]

[Prostate cancer and acute disseminated intravascular coagulation. Therapeutic management based on three cases].

作者信息

Avances Christophe, Oumaya Chokri, Granger Victoire, Dubon Olivier, Gris Jean Christophe, Culine Stéphane, Costa Pierre

机构信息

Service d'Urologie-Andrologie, Hôpital Gaston Doumergue, 5, rue Hoche, 30000 Nîmes, France.

出版信息

Prog Urol. 2003 Apr;13(2):308-12.

Abstract

Acute DIC is a rare, but life-threatening complication of metastatic prostate cancer. The authors discuss the treatment modalities in the light of three cases and a review of the recent literature. The key to treatment of DIC is treatment anti of the tumour. Androgen blockade is indicated in hormone-dependent tumours. This treatment can sometimes be completed by low-dose oral anticoagulants. Chemotherapy is the treatment of choice of acute DIC during the hormone resistance phase.

摘要

急性弥散性血管内凝血(DIC)是转移性前列腺癌一种罕见但危及生命的并发症。作者根据三例病例及近期文献综述讨论了治疗方式。治疗DIC的关键是抗肿瘤治疗。对于激素依赖性肿瘤,雄激素阻断治疗是适用的。这种治疗有时可通过低剂量口服抗凝剂来完成。化疗是激素抵抗阶段急性DIC的首选治疗方法。

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