Chargari C, Vedrine L, Bauduceau O, Le Moulec S, Fayolle M, Ceccaldi B, Houlgatte A
Service d'oncologie radiothérapie, hôpital d'instruction des armées du Val-de-Grâce, 74, boulevard de Port-Royal, 75230 Paris, France.
Prog Urol. 2008 Jan;18(1):9-13. doi: 10.1016/j.purol.2007.12.001. Epub 2008 Mar 4.
Disseminated intravascular coagulation is a rare complication of prostatic cancer evolution. Occurring on hormonorefractory phase, it remains most often infraclinic. Cases of acute, severe intravascular disseminated coagulation at first presentation are life-threatening because of hemorragic and thrombotic complications, justifying emergency medical treatment. In the light of a review of literature, we insist on epidemiological features, physiopathology and therapeutics of intravascular disseminated coagulation. In spite of a pejorative prognosis, this could help to achieve a period of remission.
弥散性血管内凝血是前列腺癌进展过程中一种罕见的并发症。它发生在激素抵抗期,多数情况下仍为亚临床状态。初诊时出现急性、严重的血管内弥散性凝血病例因出血和血栓形成并发症而危及生命,这使得紧急医疗救治成为必要。根据文献综述,我们着重阐述血管内弥散性凝血的流行病学特征、病理生理学及治疗方法。尽管预后不佳,但这有助于实现一段缓解期。