Wijnhoven Hanneke A H, Kriegsman Didi M W, Snoek Frank J, Hesselink Arlette E, de Haan Marten
Institute for Research in Extramural Medicine (E.M.G.O. Institute), Vrije Universiteit Medical Centre, Amsterdam, The Netherlands.
J Asthma. 2003 Apr;40(2):189-99. doi: 10.1081/jas-120017990.
To identify and explain differences between men and women with asthma regarding health-related quality of life (HRQoL).
A cross-sectional study was performed among 967 asthma patients recruited from general practice. Data were collected by means of a pulmonary function assessment, a face-to-face interview, and a written questionnaire.
Women with asthma reported lower scores on HRQoL in the age groups 16-34 and 56-75 years but not in the age group 35-55 years. In all age groups, women reported more severe dyspnea but had higher levels of pulmonary function. The poorer HRQoL reported by women could be explained by a more severe dyspnea and a higher level of medication use in women.
The finding that women with asthma aged 16-34 and 56-75 years report poorer HRQoL than men is not due to a more severe disease state in terms of pulmonary obstruction but does seem to be related to a more severe subjective disease state in women than in men.
识别并解释哮喘患者中男性和女性在健康相关生活质量（HRQoL）方面的差异。
对从全科医疗招募的967名哮喘患者进行了一项横断面研究。通过肺功能评估、面对面访谈和书面问卷收集数据。
16 - 34岁和56 - 75岁年龄组的哮喘女性报告的HRQoL得分较低，但35 - 55岁年龄组并非如此。在所有年龄组中，女性报告的呼吸困难更严重，但肺功能水平更高。女性报告的较差HRQoL可归因于更严重的呼吸困难和女性更高的药物使用水平。
16 - 34岁和56 - 75岁的哮喘女性报告的HRQoL比男性差这一发现，并非由于肺阻塞方面更严重的疾病状态，而似乎确实与女性比男性更严重的主观疾病状态有关。
