Lewis Michael Edward, Pitt Michael Paul Ian, Bonser Robert Stuart, Pagano Domenico
Department of Cardiac Surgery, Queen Elizabeth Hospital Medical Centre, Edgbaston, Birmingham, B15 2TH.
Heart Fail Rev. 2003 Apr;8(2):175-9. doi: 10.1023/a:1023049020136.
Recent advances in medical therapy have improved outcomes for patients with severe heart failure. However, overall survival remains poor. Transplantation is an established therapy for these patients but is limited by the large mismatch between demand and donor organ availability. Recently it has been recognised that not all ventricular dysfunction secondary to coronary artery disease is irreversible. Revascularisation in certain patients would appear to improve ventricular function. These patients are said to demonstrate myocardial "hibernation". Revascularisation in these patients may provide a further treatment option in the treatment of heart failure.
医学治疗的最新进展改善了重症心力衰竭患者的治疗效果。然而，总体生存率仍然很低。移植是这些患者的既定治疗方法，但受需求与供体器官可用性之间巨大差距的限制。最近人们认识到，并非所有继发于冠状动脉疾病的心室功能障碍都是不可逆的。某些患者的血运重建似乎可以改善心室功能。这些患者被认为表现出心肌“冬眠”。这些患者的血运重建可能为心力衰竭的治疗提供进一步的治疗选择。
