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我们是否更接近制定工作场所过敏原的阈限值? (原句存在语法错误,正确表述应该是Are we closer to developing threshold limit values for allergens in the workplace? )

I are we closer to developing threshold limit values for allergens in the workplace?

作者信息

Baur Xaver

机构信息

Institute of Occupational Medicine, University of Hamburg, Hamburg, Germany.

出版信息

Ann Allergy Asthma Immunol. 2003 May;90(5 Suppl 2):11-8. doi: 10.1016/s1081-1206(10)61642-0.

DOI:10.1016/s1081-1206(10)61642-0
PMID:12772945
Abstract

OBJECTIVE

To define threshold limit values and legally binding occupational exposure limits.

DATA SOURCES

Review of suitable literature.

STUDY SELECTION

Studies based on detailed descriptions and/or measurements of airborne allergenic dust, total allergens, or even key allergens were selected.

RESULTS

Prevalences of IgE-mediated sensitization and occupational asthma are related to the aeroallergen load in workplaces. Data to set threshold limit values for flour, latex, a-amylase, and isocyanates are already sufficiently available.

CONCLUSIONS

To optimize primary prevention in workplaces,health-based occupational exposure limits should be set for major occupational allergens.

摘要

目的

确定阈限值和具有法律约束力的职业接触限值。

数据来源

查阅相关适宜文献。

研究选择

选取基于对空气中致敏性粉尘、总变应原甚至关键变应原进行详细描述和/或测量的研究。

结果

IgE介导的致敏反应和职业性哮喘的患病率与工作场所的空气变应原负荷相关。现已具备足够数据来设定面粉、乳胶、α淀粉酶和异氰酸酯的阈限值。

结论

为优化工作场所的一级预防,应为主要职业性变应原设定基于健康的职业接触限值。

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I are we closer to developing threshold limit values for allergens in the workplace?我们是否更接近制定工作场所过敏原的阈限值? (原句存在语法错误,正确表述应该是Are we closer to developing threshold limit values for allergens in the workplace? )
Ann Allergy Asthma Immunol. 2003 May;90(5 Suppl 2):11-8. doi: 10.1016/s1081-1206(10)61642-0.
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Exposure-response relationships of occupational inhalative allergens.职业性吸入性变应原的暴露-反应关系。
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Experiences from occupational exposure limits set on aerosols containing allergenic proteins.关于含致敏蛋白气溶胶职业接触限值的经验。
Ann Occup Hyg. 2012 Oct;56(8):888-900. doi: 10.1093/annhyg/mes035. Epub 2012 Jul 28.
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Management of work-related asthma: guidelines and challenges.职业性哮喘的管理:指南与挑战
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Curr Allergy Asthma Rep. 2012 Jun;12(3):221-31. doi: 10.1007/s11882-012-0259-2.
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Environmental isocyanate-induced asthma: morphologic and pathogenetic aspects of an increasing occupational disease.环境性异氰酸酯诱导性哮喘:一种日益增多的职业性疾病的形态学和发病机制方面。
Int J Environ Res Public Health. 2011 Sep;8(9):3672-87. doi: 10.3390/ijerph8093672. Epub 2011 Sep 9.
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Occupational asthma: etiologies and risk factors.职业性哮喘:病因和危险因素。
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The role of inhalant food allergens in occupational asthma.吸入性食物过敏原在职业性哮喘中的作用。
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Food hypersensitivity by inhalation.吸入性食物过敏
Clin Mol Allergy. 2009 Feb 20;7:4. doi: 10.1186/1476-7961-7-4.
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Skin exposure to isocyanates: reasons for concern.皮肤接触异氰酸酯:令人担忧的原因。
Environ Health Perspect. 2007 Mar;115(3):328-35. doi: 10.1289/ehp.9557. Epub 2006 Nov 28.
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