Naqvi Tasneem Z
Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center and UCLA School of Medicine, Los Angeles, CA, USA.
Rev Cardiovasc Med. 2003 Spring;4(2):81-99.
Congestive heart failure (CHF) is the leading cause of cardiac morbidity and mortality from cardiovascular disease. Although left ventricular (LV) diastolic dysfunction occurs in all patients with systolic dysfunction and CHF, fully one third of patients have CHF due to isolated diastolic dysfunction. Despite this, the role of diastolic function in heart failure is underappreciated by many primary care physicians and even by cardiologists. Development and validation of several noninvasive Doppler echocardiographic techniques that are relatively load-independent have made echocardiography the clinical standard for the assessment of LV diastolic function. Echocardiography uses portable equipment; is readily accessible and safe; and excludes other causes of CHF, such as valvular heart disease, pericardial disease, and systolic dysfunction. This review summarizes the use of recently developed Doppler techniques for the assessment of LV diastolic function, as well as their application in assessing prognosis and in guiding therapy for various cardiovascular disease states.
充血性心力衰竭（CHF）是心血管疾病导致心脏发病和死亡的主要原因。虽然所有收缩功能障碍和CHF患者都会出现左心室（LV）舒张功能障碍，但足足有三分之一的患者因单纯舒张功能障碍而发生CHF。尽管如此，舒张功能在心力衰竭中的作用仍未得到许多初级保健医生甚至心脏病专家的充分重视。几种相对不受负荷影响的非侵入性多普勒超声心动图技术的开发和验证，使超声心动图成为评估LV舒张功能的临床标准。超声心动图使用便携式设备；易于操作且安全；并且排除了CHF的其他原因，如瓣膜性心脏病、心包疾病和收缩功能障碍。本综述总结了最近开发的多普勒技术在评估LV舒张功能方面的应用，以及它们在评估预后和指导各种心血管疾病状态治疗中的应用。
