Xi Zhu-ting, Shan Chang-min, Jiang Xue-lian, Luan Xi-ying, Li Ke-ke
Binzhou Medical College, Binzhou 256603, Shandong, China.
Zhongguo Zhong Yao Za Zhi. 2002 Dec;27(12):929-32.
To study the effects of rhizoma sparganii and radices zedoariae on hepatic fibrosis.
The rat immunohepatic fibrosis model was made by intraperitoneal injection of porcine serum and treated with rhizoma sparganii and radices zedoariae. The ALT, GGT, TP, ALb, A/G, IVC, LN, HA and the pathological change of the liver were observed.
Rhizoma sparganii and radices zedoariae could increase TP, ALb, A/G, decrease ALT, GGT, IVC, LN, HA and improve the pathological change.
Rhizoma sparganii and radices zedoariae can protect hepatic cells, alleviate degeneration and necrosis, recover structure and function, and reduce the proliferation of fibrous tissue.
研究三棱和莪术对肝纤维化的影响。
通过腹腔注射猪血清制备大鼠免疫性肝纤维化模型，并用三棱和莪术进行治疗。观察谷丙转氨酶（ALT）、γ-谷氨酰转肽酶（GGT）、总蛋白（TP）、白蛋白（ALb）、白蛋白/球蛋白比值（A/G）、透明质酸（IVC）、层粘连蛋白（LN）、透明质酸（HA）及肝脏病理变化。
三棱和莪术可使TP、ALb、A/G升高，使ALT、GGT、IVC、LN、HA降低，并改善病理变化。
三棱和莪术可保护肝细胞，减轻变性和坏死，恢复结构和功能，减少纤维组织增生。
