Barnes R W, Rittenhouse E A, Miller E V
Chest. 1976 Jul;70(1):48-50. doi: 10.1378/chest.70.1.48.
Rate-corrected velocity upstroke time (VUT) was calculated from analogue Doppler ultrasound recordings of axillary artery blood flow velocity in 25 patients with aortic stenosis documented by cardiac catheterization and in 14 normal individuals. The mean VUT in normal individuals was 0.11 +/- 0.02 second (+/- 1 SD), which was significantly lower than that of patients with aortic stenosis: 0.15 +/- 0.05 second (P less than 0.005). The VUT correlated with the aortic valve index and the aortic valve mean pressure gradient with correlation coefficients of 0.62 and 0.64, respectively (P less than 0.005). Arterial blood flow velocity assessment by Doppler ultrasound may be a useful noninvasive technique to evaluate patients with aortic valve disease.
通过对25例经心导管检查证实患有主动脉瓣狭窄的患者以及14名正常个体的腋动脉血流速度进行模拟多普勒超声记录，计算出心率校正的速度上升时间（VUT）。正常个体的平均VUT为0.11±0.02秒（±1标准差），显著低于主动脉瓣狭窄患者的0.15±0.05秒（P<0.005）。VUT与主动脉瓣指数和主动脉瓣平均压力阶差相关，相关系数分别为0.62和0.64（P<0.005）。通过多普勒超声评估动脉血流速度可能是一种评估主动脉瓣疾病患者的有用的非侵入性技术。
