Lee Anne J, Rochtchina Elena, Wang Jie Jin, Healey Paul R, Mitchell Paul
Department of Ophthalmology, Center for Vision Research, University of Sydney, Westmead Hospital, Hawkesbury Road, Westmead, NSW 2145, Australia.
J Glaucoma. 2003 Jun;12(3):209-12. doi: 10.1097/00061198-200306000-00005.
To assess the relationship between smoking and intraocular pressure.
The Blue Mountains Eye Study examined 3654 residents aged 49 years and older in an area west of Sydney, Australia from 1992 to 1994. A trained interviewer collected a detailed history of smoking. Intraocular pressure was measured using Goldmann applanation tonometry; as the correlation between right and left eyes was very high, only right-eye data are presented. Participants using glaucoma medications or who had evidence of previous cataract surgery were excluded.
Current smokers (15.8% of participants) had slightly higher mean intraocular pressures (16.34 mm Hg) than nonsmokers (16.04 mm Hg). Intraocular pressure (in the right eye) was significantly associated with current smoking, after adjusting for age and sex (P = 0.03). This association remained unchanged after simultaneous adjustment for other variables associated with intraocular pressure, including blood pressure, diabetes, myopia, glaucoma, family history, and pseudoexfoliation (P = 0.02).
This study identified a modest cross-sectional positive association between current smoking and intraocular pressure.
评估吸烟与眼压之间的关系。
蓝山眼研究于1992年至1994年对澳大利亚悉尼以西一个地区的3654名49岁及以上居民进行了调查。一名经过培训的访员收集了详细的吸烟史。使用戈德曼压平眼压计测量眼压；由于左右眼之间的相关性非常高，仅呈现右眼数据。排除使用青光眼药物或有既往白内障手术证据的参与者。
当前吸烟者（占参与者的15.8%）的平均眼压（16.34毫米汞柱）略高于不吸烟者（16.04毫米汞柱）。在调整年龄和性别后，眼压（右眼）与当前吸烟显著相关（P = 0.03）。在同时调整与眼压相关的其他变量（包括血压、糖尿病、近视、青光眼、家族史和假性剥脱）后，这种关联保持不变（P = 0.02）。
本研究发现当前吸烟与眼压之间存在适度的横断面正相关。
