Rosini S, Trallori L
Farmaco Sci. 1976 Jun;31(6):403-11.
2-5-Dibromo-2-(beta-naphtyl)indan-1,3-dione (43/63) and 4-bromo-2-phenylindan-1,3-dione (43/13) are two interesting members of a series of "indandione" derivatives which possess an antiinflammatory activity (in the following tests: carrageenin induced rat hind paw edema, cotton pellets granuloma and chronic adjuvant arthritis). The two drugs are devoided of anticoagulant activity and their antiinflammatory effect is not adrenalmediated.
2-5-二溴-2-(β-萘基)茚满-1,3-二酮(43/63)和4-溴-2-苯基茚满-1,3-二酮(43/13)是一系列具有抗炎活性的“茚二酮”衍生物中的两个有趣成员(在以下试验中:角叉菜胶诱导的大鼠后爪水肿、棉球肉芽肿和慢性佐剂性关节炎)。这两种药物没有抗凝活性,且它们的抗炎作用不是由肾上腺介导的。