Pelosi Paolo, Severgnini Paolo, Aspesi Michele, Gamberoni Chiara, Chiumello Davide, Fachinetti Cecilia, Introzzi Lorenzo, Antonelli Massimo, Chiaranda Maurizio
Università degli Studi dell'Insubria, Dipartimento di Scienze Cliniche e Biologiche, Azienda Ospedaliera Universitaria, Ospedale di Circolo e Fondazione Macchi, Varese, Italy.
Eur J Emerg Med. 2003 Jun;10(2):79-86. doi: 10.1097/00063110-200306000-00002.
Non-invasive positive pressure ventilation is increasingly used as a first-line treatment for respiratory failure. Non-invasive positive pressure ventilation can reduce the complications of endotracheal intubation such as barotrauma, nosocomial infections and the need for sedation. Non-invasive positive pressure ventilation has been shown to reduce the rate of endotracheal intubation in acute cardiogenic pulmonary oedema (27%), in chronic obstructive pulmonary disease (21%), and in acute respiratory failure (17%). Non-invasive positive pressure ventilation can be successfully delivered in the emergency department or in the general ward. However, the criteria for interrupting non-invasive positive pressure ventilation must be stricter (i.e. failure to improve gas exchange within 30 min) than in the general ward. One of the main reasons for the failure of non-invasive positive pressure ventilation lies in the technical problems caused by the face mask. We recently developed a new interface, the 'helmet', to deliver non-invasive positive pressure ventilation. When using the helmet instead of a face mask an increase of 10 cm H(2)O of pressure support and a fast pressurization rate are recommended. In a lung model and in healthy individuals the helmet reduced inspiratory effort. In hypoxemic patients the helmet reduced the intubation rate and the incidence of face mask-related complications. We believe that the helmet can extend the application of non-invasive positive pressure ventilation in different categories of patients with respiratory failure.
无创正压通气越来越多地被用作呼吸衰竭的一线治疗方法。无创正压通气可减少气管插管的并发症,如气压伤、医院感染和镇静需求。无创正压通气已被证明可降低急性心源性肺水肿(27%)、慢性阻塞性肺疾病(21%)和急性呼吸衰竭(17%)患者的气管插管率。无创正压通气可在急诊科或普通病房成功实施。然而,中断无创正压通气的标准必须比普通病房更严格(即30分钟内气体交换无改善)。无创正压通气失败的主要原因之一在于面罩引起的技术问题。我们最近开发了一种新的界面——“头盔”,用于实施无创正压通气。使用头盔代替面罩时,建议增加10 cm H₂O的压力支持并采用快速增压速率。在肺模型和健康个体中,头盔可减少吸气努力。在低氧血症患者中,头盔可降低插管率和面罩相关并发症的发生率。我们认为,头盔可扩大无创正压通气在不同类型呼吸衰竭患者中的应用。