Page Roy C
School of Dentistry, School of Medicine, University of Washington, Seattle, Washington, USA.
Compend Contin Educ Dent. 2002 May;23(5 Suppl):11-4.
Major advances have been made in our basic understanding of periodontal disease during the last decade. Pathways whereby bacteria destroy the periodontal connective tissues and alveolar bone have been elucidated. The manner in which various risk factors alter these pathways to enhance risk and amplify the onset and progression of disease is becoming clearer. Furthermore, a strong link between periodontitis and potentially fatal systemic diseases and conditions has been demonstrated. These advances in knowledge have led to the development of new approaches to treatment that enhance our capacity to prevent and control oral infections and to decrease potential systemic disease consequences.
在过去十年里，我们对牙周病的基础认识取得了重大进展。细菌破坏牙周结缔组织和牙槽骨的途径已被阐明。各种风险因素改变这些途径以增加风险并放大疾病的发生和进展的方式正变得越来越清晰。此外，牙周炎与潜在致命的全身性疾病和病症之间的紧密联系已得到证实。这些知识上的进展导致了新的治疗方法的发展，提高了我们预防和控制口腔感染以及减少潜在全身性疾病后果的能力。
