Vajrabhaya La-Ongthong, Benjasupattananan Supranee, Sappayatosok Kraisorn, Dechosilpa Vittawin, Korsuwannawong Suwanna, Sirikururat Papatpong
College of Dental Medicine, Rangsit University, Pathumthani 12000, Thailand.
Research Office, Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand.
Dent J (Basel). 2024 Nov 22;12(12):378. doi: 10.3390/dj12120378.
This study investigated the efficacy of a herbal toothpaste containing (test group) compared with a sodium bicarbonate toothpaste (active control group) and a standard toothpaste (benchmark group) on periodontitis treatment outcomes. Fifty-four periodontitis patients were randomly allocated into three groups. The patients received mechanical instrumentation and instruction on oral hygiene using a toothbrush with the toothpastes and dental floss. The patients were evaluated at baseline (T0), week 4 (T1), and week 12 (T2) after complete scaling and root planing. During the visits, the plaque score (PS), bleeding on probing (BOP), probing depth (PD) and clinical attachment level (CAL) were assessed and analyzed. The comparison groups had similar PS and BOP means at baseline. At T1 and T2, both scores were reduced; however, there was no significant difference in PS among the three groups. A significant reduction in BOP among the groups was observed ( < 0.01) at T1. The PDs in all groups were significantly reduced after treatment. The CAL reduction was greater in the test group compared with the benchmark and the active control group. Furthermore, there was no significant difference in the mean CAL among time points in the benchmark and the active control groups. The herbal toothpaste containing significantly decreased gingival inflammation, PD, and CAL over the standard and active control toothpaste in periodontitis patients during active periodontal treatment.
本研究调查了一种含[具体成分]的草本牙膏（试验组）与碳酸氢钠牙膏（阳性对照组）和标准牙膏（基准组）相比，在牙周炎治疗效果方面的功效。54名牙周炎患者被随机分为三组。患者接受了机械器械治疗，并接受了使用牙膏和牙线的牙刷进行口腔卫生指导。在完成龈下刮治和根面平整后的基线期（T0）、第4周（T1）和第12周（T2）对患者进行评估。在就诊期间，评估并分析了菌斑评分（PS）、探诊出血（BOP）、探诊深度（PD）和临床附着水平（CAL）。各比较组在基线时的PS和BOP平均值相似。在T1和T2时，两项评分均降低；然而，三组之间的PS没有显著差异。在T1时观察到各组间BOP有显著降低（<0.01）。治疗后所有组的PD均显著降低。试验组的CAL降低幅度大于基准组和阳性对照组。此外，基准组和阳性对照组在各时间点的平均CAL没有显著差异。在积极的牙周治疗期间，含[具体成分]的草本牙膏与标准牙膏和阳性对照牙膏相比，能显著降低牙周炎患者的牙龈炎症、PD和CAL。
