高度对齐的DNA纳米线的转移印刷

Transfer-printing of highly aligned DNA nanowires.

作者信息

Nakao Hidenobu, Gad Muhammed, Sugiyama Shigeru, Otobe Kazunori, Ohtani Toshio

机构信息

National Agricultural Research Organization, 3-1-1 Kannondai, Tsukuba, Ibaraki 305-8518, Japan.

出版信息

J Am Chem Soc. 2003 Jun 18;125(24):7162-3. doi: 10.1021/ja034185w.

DOI:10.1021/ja034185w

PMID:12797774

Abstract

We developed a simple method of reproducibly creating highly aligned DNA nanowires without any surface modifications or special equipment. Stretched DNA molecules initially present on the PDMS sheet were transferred onto another surface using transfer-printing (TP). Fluorescent microscopic and atomic force microscopic images revealed that many DNA molecules were highly aligned on surfaces after TP. Furthermore, it was also possible to realize the two-dimensional assembly of DNA nanowires by repeating TP.

摘要

我们开发了一种简单的方法，可在无需任何表面修饰或特殊设备的情况下，可重复地创建高度排列的DNA纳米线。最初存在于聚二甲基硅氧烷（PDMS）片材上的拉伸DNA分子通过转印（TP）转移到另一个表面上。荧光显微镜和原子力显微镜图像显示，转印后许多DNA分子在表面上高度排列。此外，通过重复转印还可以实现DNA纳米线的二维组装。