Hahn R, Essén P, Wernerman J
Department of Anaesthesiology, Huddinge University Hospital, Sweden.
Scand J Urol Nephrol. 1992;26(3):235-9. doi: 10.3109/00365599209180875.
The concentrations of amino acids in plasma and skeletal muscle were measured 1 and 4 hours after transurethral prostatic resection in three patients who developed symptoms of the transurethral resection syndrome. The irrigating solution contained 1.5% of glycine and 1% of ethanol. The concentrations of glycine in plasma and muscle were equal within an hour of the operation, and at four hours the abnormally high glycine concentration persisted in muscle, though it had decreased rapidly in plasma. Our data suggest that skeletal muscle is a quantitatively important reservoir for glycine when this amino acid is supplied in potentially toxic amounts, but that the plasma glycine concentration returns to normal as the patient's clinical condition improves.
在三名出现经尿道前列腺切除综合征症状的患者中，于经尿道前列腺切除术后1小时和4小时测量了血浆和骨骼肌中的氨基酸浓度。冲洗液含有1.5%的甘氨酸和1%的乙醇。手术1小时内血浆和肌肉中的甘氨酸浓度相等，4小时时，尽管血浆中甘氨酸浓度迅速下降，但肌肉中异常高的甘氨酸浓度仍持续存在。我们的数据表明，当以潜在毒性量供应这种氨基酸时，骨骼肌是甘氨酸在数量上的重要储存库，但随着患者临床状况的改善，血浆甘氨酸浓度会恢复正常。
