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孟德尔与现代遗传学:当今的遗产

Mendel and modern genetics: the legacy for today.

作者信息

Allen Garland E

机构信息

Department of Biology, Washington University, St Louis, MO 63130, USA.

出版信息

Endeavour. 2003 Jun;27(2):63-8. doi: 10.1016/s0160-9327(03)00065-6.

Abstract

The legacy of Mendel's pioneering studies of hybridization in the pea continues to influence the way we understand modern genetics. But what sort of picture did Mendel himself have of his work and its ultimate uses, and how does that picture compare with the collection of ideas and methodologies that was put forward in his name and later became known as 'Mendelism'? With genetics standing at the center of our present biomedical and biotechnological research, an examination of the history of our concepts in the field can help us better understand what we should and should not expect from current genetic claims. For that enterprise there is no better starting place than Mendel himself.

摘要

孟德尔对豌豆杂交的开创性研究遗产,至今仍在影响我们理解现代遗传学的方式。但孟德尔本人对自己的工作及其最终用途有着怎样的看法呢?他的看法与以他的名义提出、后来被称为“孟德尔主义”的一系列思想和方法相比又如何呢?遗传学处于我们当前生物医学和生物技术研究的核心,审视该领域概念的历史有助于我们更好地理解对于当前的基因主张,我们应该期待什么,不应该期待什么。对于这项事业来说,没有比孟德尔本人更好的起点了。

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