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[月经性偏头痛的药物治疗]

[Medical therapy for menstrual migraine].

作者信息

Pfaffenrath V, Goes A

机构信息

Neurologe, Leopoldstrasse 59/II, D-80 802 München.

出版信息

Schmerz. 1996 Jun 17;10(3):146-8. doi: 10.1007/s004829600043.

Abstract

A menstrual migraine occurs in approximately 7-10 % of women suffering from migraine. The migraine occurs from 2 days before until 3 days after the end of the menstrual period. The choice of treatment depends on the duration of the attack, which ranges from 3 to 7 days. An attack of up to 3 days duration should be treated with acetylsalicylic acid, ergotamine tartrate or naproxen, each in combination with an antiemetic (domperidone, metoclopramide). If there is no response, sumatriptan can be administered orally (25-100 mg) or subcutaneously (6 mg). In the attacks continue for more than 3 days, short-term prophylaxis with naproxen or the application of an estrogen-containing patch is indicated. Neither ovulation inhibitors nor traditional migraine prophylaxis has an influence on menstrual migraine. Patients should keep a headache diary. Short-term prophylaxis with ergotamine tartrate or tamoxifen is obsolete.

摘要

月经性偏头痛约发生于7% - 10%的偏头痛女性患者中。偏头痛发作于月经期结束前2天直至结束后3天。治疗方法的选择取决于发作持续时间,发作持续时间为3至7天。持续时间达3天的发作,应使用乙酰水杨酸、酒石酸麦角胺或萘普生进行治疗,每种药物均与一种止吐药(多潘立酮、甲氧氯普胺)联合使用。如果没有反应,可口服舒马曲坦(25 - 100毫克)或皮下注射(6毫克)。若发作持续超过3天,则需使用萘普生进行短期预防或应用含雌激素的贴片。排卵抑制剂和传统的偏头痛预防性用药对月经性偏头痛均无影响。患者应记录头痛日记。使用酒石酸麦角胺或他莫昔芬进行短期预防已过时。

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