Annibale B, Capurso G, Delle Fave G
Department of Digestive and Liver Disease, II Medical School, Sant'Andrea Hospital, University La Sapienza, Rome, Italy.
Dig Liver Dis. 2003 Apr;35(4):288-95. doi: 10.1016/s1590-8658(03)00067-7.
Iron deficiency anaemia is generally considered a sign of occult bleeding from the gastrointestinal tract, and standard care therefore includes evaluation of the gastrointestinal tract to rule out possible bleeding sites. However, it is often overlooked that iron deficiency anaemia may be the result of an imbalance between iron loss and iron intake, and may also be due to reduced absorption of iron from food, i.e., coeliac disease. The absorption of alimentary iron is not a simple process and the stomach plays a major role in this process of iron "digestion". This review presents evidence linking iron deficiency anaemia to gastric conditions that lead to reduced acid secretion, such as, for example, gastric surgery, atrophic body gastritis and Helicobacter pylori gastritis.
缺铁性贫血通常被认为是胃肠道隐匿性出血的迹象，因此标准治疗包括对胃肠道进行评估，以排除可能的出血部位。然而，人们常常忽视缺铁性贫血可能是铁流失与铁摄入失衡的结果，也可能是由于食物中铁吸收减少，即乳糜泻所致。膳食铁的吸收并非一个简单的过程，胃在这个铁“消化”过程中起着主要作用。这篇综述提供了证据，将缺铁性贫血与导致胃酸分泌减少的胃部疾病联系起来，例如胃手术、胃体萎缩性胃炎和幽门螺杆菌胃炎。
