生物膜形成的基因组学和蛋白质组学
The genomics and proteomics of biofilm formation.
作者信息
Sauer Karin
机构信息
State University of New York at Binghamton, 104 Science III, Vestal Parkway East, Binghamton, NY 13902, USA.
出版信息
Genome Biol. 2003;4(6):219. doi: 10.1186/gb-2003-4-6-219. Epub 2003 May 27.
Abstract
Bacterial communities that are attached to a surface, so-called biofilms, and their inherent resistance to antimicrobial agents are a cause of many persistent and chronic bacterial infections. Recent genomic and proteomic studies have identified many of the genes and gene products differentially expressed during biofilm formation, revealing the complexity of this developmental process.
摘要
附着于表面的细菌群落，即所谓的生物膜，以及它们对抗菌剂的固有抗性是许多持续性和慢性细菌感染的原因。最近的基因组和蛋白质组学研究已经鉴定出许多在生物膜形成过程中差异表达的基因和基因产物，揭示了这一发育过程的复杂性。
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