Guilbaud J
Centre des Brûlés, Hôpital Percy, Clamart, France.
Burns. 1992 Oct;18(5):419-22. doi: 10.1016/0305-4179(92)90044-u.
Eleven European burns centres in five countries (Belgium, England, Germany, Italy, Switzerland) participated in a prospective, randomized clinical trial comparing a new wound dressing Inerpan with conventional dressings such as petroleum jelly gauze, petroleum jelly gauze with antibiotics and silver sulphadiazine cream. The indication was partial skin thickness burns and 62 patients were included. In each patient, two similar lesions (with respect to depth and surface area) were compared, one being treated with Inerpan, the other one with a control dressing. The following parameters were studied: healing time, quality of healing, intensity of pain, local tolerance and frequency of dressing changes. Analysis of the results showed that Inerpan-treated sites healed faster than conventional ones, and were associated with a highly significant reduction of pain. The frequency of dressing changes was greatly reduced and the local tolerance was good.
来自五个国家（比利时、英国、德国、意大利、瑞士）的11个欧洲烧伤中心参与了一项前瞻性随机临床试验，该试验比较了一种新型伤口敷料Inerpan与传统敷料，如凡士林纱布、含抗生素的凡士林纱布和磺胺嘧啶银乳膏。入选标准为浅度皮肤烧伤，共纳入62例患者。在每位患者身上，比较两个相似的伤口（在深度和表面积方面），一个用Inerpan治疗，另一个用对照敷料治疗。研究了以下参数：愈合时间、愈合质量、疼痛强度、局部耐受性和换药频率。结果分析表明，用Inerpan治疗的伤口比传统方法愈合得更快，且疼痛显著减轻。换药频率大大降低，局部耐受性良好。
