Wasiak Jason, Cleland Heather
Epworth Healthcare, Richmond, Australia.
BMJ Clin Evid. 2015 Jul 14;2015:1903.
Burns are classified according to depth. This overview concerns the treatments for partial-thickness burns, which can be expected or have the potential to heal spontaneously (superficial partial-thickness and mid-dermal partial-thickness burns). Injuries that involve the deeper part of the dermis and require surgical treatments to achieve healing are not the focus of this overview.
We conducted a systematic overview and aimed to answer the following clinical question: What are the effects of treatments for partial-thickness burns? We searched: Medline, Embase, The Cochrane Library, and other important databases up to January 2014 (Clinical Evidence overviews are updated periodically; please check our website for the most up-to-date version of this review).
At this update, searching of electronic databases retrieved 322 studies. After deduplication and removal of conference abstracts, 193 records were screened for inclusion in the overview. Appraisal of titles and abstracts led to the exclusion of 160 studies and the further review of 33 full publications. Of the 33 full articles evaluated, two systematic reviews and two RCTs were added at this update. We performed a GRADE evaluation for 30 PICO combinations.
In this systematic overview, we categorised the efficacy for 10 interventions, based on information relating to the effectiveness and safety of alginate dressing, biosynthetic dressing, chlorhexidine-impregnated paraffin gauze dressing, hydrocolloid dressing, hydrogel dressing, paraffin gauze dressing, polyurethane film, silicone-coated nylon dressing, silver-impregnated dressing, and silver sulfadiazine cream.
烧伤按深度分类。本综述涉及浅度烧伤的治疗,浅度烧伤有望或有自行愈合的可能(浅Ⅱ度和深Ⅱ度烧伤)。涉及真皮深层且需要手术治疗才能愈合的损伤并非本综述的重点。
我们进行了一项系统综述,旨在回答以下临床问题:浅度烧伤的治疗效果如何?我们检索了:截至2014年1月的医学期刊数据库(Medline)、荷兰医学文摘数据库(Embase)、考克兰图书馆及其他重要数据库(临床证据综述会定期更新;请查看我们的网站获取本综述的最新版本)。
在本次更新时,检索电子数据库共获得322项研究。在去除重复项和会议摘要后,筛选出193条记录以纳入综述。对标题和摘要进行评估后,排除了160项研究,对33篇全文进行了进一步审查。在本次更新中,对评估的33篇全文添加了两项系统评价和两项随机对照试验。我们对30种PICO组合进行了GRADE评估。
在本系统综述中,我们根据藻酸盐敷料、生物合成敷料、含氯己定石蜡纱布敷料、水胶体敷料、水凝胶敷料、石蜡纱布敷料、聚氨酯薄膜、硅胶涂层尼龙敷料、含银敷料和磺胺嘧啶银乳膏的有效性和安全性信息,对10种干预措施的疗效进行了分类。