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钝性胸部创伤患者长期通气支持的预测

Prediction of prolonged ventilatory support in blunt thoracic trauma patients.

作者信息

Dimopoulou Ioanna, Anthi Anastasia, Lignos Michalis, Boukouvalas Efstratios, Evangelou Evangelos, Routsi Christina, Mandragos Konstantinos, Roussos Charis

机构信息

Department of Critical Care Medicine, Evangelismos Hospital, Athens, Greece.

出版信息

Intensive Care Med. 2003 Jul;29(7):1101-5. doi: 10.1007/s00134-003-1813-0. Epub 2003 Jun 12.

Abstract

OBJECTIVE

To identify predictors of prolonged (>7 days) mechanical ventilation (MV) in patients with blunt thoracic trauma.

DESIGN

Prospective analysis of consecutive patients.

SETTING

Adult intensive care unit (ICU) in a teaching, tertiary-care hospital.

PATIENTS AND PARTICIPANTS

Sixty-nine patients (53 men, 16 women) with thoracic trauma having a median age of 35 (range 17-85) years and a median injury severity score (ISS) of 29 (range 14-41) were enrolled in the present study. Associated injuries included head-neck (77%), extremities (72%), external (67%), abdomen-pelvis (67%), and face (55%).

INTERVENTIONS

Patient surveillance and data collection.

MEASUREMENTS AND RESULTS

Thirty-three (48%) of the 69 patients required prolonged ventilatory support, ranging in duration from 8 to 38 (median 18) days. Logistic regression analysis revealed that advancing age (odds ratio=1.04, p=0.04), severity of head injury (odds ratio=1.92, p=0.008), and bilateral thoracic injuries (odds ratio=12.80, p<0.0001) were significant and independent predictors of long-lasting MV. In contrast, gender, injuries affecting the other body regions (face, abdomen-pelvis, extremities, and external), laparotomy in patients with abdominal injury, or PaO(2)/FIO(2) on admission in the ICU, were unrelated to prolonged MV.

CONCLUSIONS

In thoracic trauma patients admitted in the ICU, prolonged mechanical ventilation was primarily determined by presence of bilateral chest injuries, age, and degree of neurotrauma. This information may help in planning the long-term care of such patients.

摘要

目的

确定钝性胸部创伤患者机械通气时间延长(>7天)的预测因素。

设计

对连续患者进行前瞻性分析。

地点

一所教学型三级医院的成人重症监护病房(ICU)。

患者和参与者

本研究纳入了69例胸部创伤患者(53例男性,16例女性),中位年龄35岁(范围17 - 85岁),中位损伤严重程度评分(ISS)为29分(范围14 - 41分)。相关损伤包括头颈部(77%)、四肢(72%)、体表(67%)、腹部 - 骨盆(67%)和面部(55%)。

干预措施

患者监测和数据收集。

测量指标及结果

69例患者中有33例(48%)需要延长通气支持,持续时间为8至38天(中位时间18天)。逻辑回归分析显示,年龄增长(比值比 = 1.04,p = 0.04)、头部损伤严重程度(比值比 = 1.92,p = 0.008)和双侧胸部损伤(比值比 = 12.80,p < 0.0001)是长期机械通气的显著且独立的预测因素。相比之下,性别、影响其他身体部位(面部、腹部 - 骨盆、四肢和体表)的损伤、腹部损伤患者的剖腹手术或入住ICU时的动脉血氧分压/吸入氧分数值(PaO₂/FIO₂)与机械通气时间延长无关。

结论

在入住ICU的胸部创伤患者中,机械通气时间延长主要由双侧胸部损伤、年龄和神经创伤程度决定。这些信息可能有助于规划此类患者的长期护理。

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