Tsai Theodore L, Fridsma Douglas B, Gatti Guido
Center for Biomedical Informatics and Department of Medicine, University of Pittsburgh, Suite 8084 Forbes Tower, 3600 Meyran Avenue, Pittsburgh, PA 15261, USA.
J Am Med Inform Assoc. 2003 Sep-Oct;10(5):478-83. doi: 10.1197/jamia.M1279. Epub 2003 Jun 4.
The aim of this study was to determine the effect that the computer interpretation (CI) of electrocardiograms (EKGs) has on the accuracy of resident (noncardiologist) physicians reading EKGs.
A randomized, controlled trial was conducted in a laboratory setting from February through June 2001, using a two-period crossover design with matched pairs of subjects randomly assigned to sequencing groups.
Subjects' interpretive accuracy of discrete, cardiologist-determined EKG findings were measured as judged by a board-certified internist.
Without the CI, subjects interpreted 48.9% (95% confidence interval, 45.0% to 52.8%) of the findings correctly. With the CI, subjects interpreted 55.4% (51.9% to 58.9%) correctly (p < 0.0001). When the CIs that agreed with the gold standard (Correct CIs) were not included, 53.1% (47.7% to 58.5%) of the findings were interpreted correctly. When the correct CI was included, accuracy increased to 68.1% (63.2% to 72.7%; p < 0.0001). When computer advice that did not agree with the gold standard (Incorrect CI) was not provided to the subjects, 56.7% (48.5% to 64.5%) of findings were interpreted correctly. Accuracy dropped to 48.3% (40.4% to 56.4%) when the incorrect computer advice was provided (p = 0.131). Subjects erroneously agreed with the incorrect CI more often when it was presented with the EKG 67.7% (57.2% to 76.7%) than when it was not 34.6% (23.8% to 47.3%; p < 0.0001).
Computer decision support systems can generally improve the interpretive accuracy of internal medicine residents in reading EKGs. However, subjects were influenced significantly by incorrect advice, which tempers the overall usefulness of computer-generated advice in this and perhaps other areas.
本研究旨在确定心电图(EKG)的计算机解读(CI)对住院医师(非心脏病专家)阅读EKG准确性的影响。
2001年2月至6月在实验室环境中进行了一项随机对照试验,采用两阶段交叉设计,将配对的受试者随机分配到测序组。
由一名获得董事会认证的内科医生判断受试者对心脏病专家确定的离散EKG结果的解读准确性。
在没有CI的情况下,受试者正确解读了48.9%(95%置信区间,45.0%至52.8%)的结果。有了CI后,受试者正确解读的比例为55.4%(51.9%至58.9%)(p<0.0001)。当不包括与金标准一致的CI(正确CI)时,53.1%(47.7%至58.5%)的结果被正确解读。当包括正确的CI时,准确性提高到68.1%(63.2%至72.7%;p<0.0001)。当未向受试者提供与金标准不一致的计算机建议(错误CI)时,56.7%(48.5%至64.5%)的结果被正确解读。当提供错误的计算机建议时,准确性降至48.3%(40.4%至56.4%)(p=0.131)。当错误的CI与EKG一起呈现时,受试者错误地同意错误CI的频率更高,为67.7%(57.2%至76.7%),而不呈现时为34.6%(23.8%至47.3%;p<0.0001)。
计算机决策支持系统通常可以提高内科住院医师阅读EKG的解读准确性。然而,受试者受到错误建议的显著影响,这削弱了计算机生成建议在该领域及其他可能领域的整体实用性。