Moyo S R, Maeland J A, Munemo E S
Department of Medical Microbiology, University of Zimbabwe, Harare, Zimbabwe.
Cent Afr J Med. 2001 Sep-Oct;47(9-10):226-9.
To establish the susceptibility of Zimbabwean GBS strains isolated from hospitalised patients to four antibiotics.
Cross sectional survey.
Four regions of Zimbabwe (Bindura, Bulawayo, Harare, and Masvingo).
113 GBS isolates from hospitalised patients in Bindura, Bulawayo, Harare and Masvingo, of whom most were suffering from infectious diseases.
All isolates were tested for their susceptibility to clindamycin, erythromycin, penicillin and tetracycline.
All isolates were 100% sensitive to clindamycin, 98% to penicillin, 86% to erythromycin; 2% of the isolates showed intermediate susceptibility to penicillin and 100% showed resistance to tetracycline.
Penicillin is still the antibiotic of choice for treatment of GBS infections and for intrapartum chemoprophylaxis in Zimbabwe. For patients who are allergic to penicillin, clindamycin will be the drug of choice for both treatment and/or chemoprophylactic use in Zimbabwe.
确定从住院患者中分离出的津巴布韦B族链球菌菌株对四种抗生素的敏感性。
横断面调查。
津巴布韦的四个地区（宾杜拉、布拉瓦约、哈拉雷和马斯温戈）。
从宾杜拉、布拉瓦约、哈拉雷和马斯温戈的住院患者中分离出的113株B族链球菌，其中大多数患有传染病。
检测所有分离株对克林霉素、红霉素、青霉素和四环素的敏感性。
所有分离株对克林霉素的敏感性为100%，对青霉素为98%，对红霉素为86%；2%的分离株对青霉素表现出中度敏感性，100%对四环素耐药。
在津巴布韦，青霉素仍是治疗B族链球菌感染和产时化学预防的首选抗生素。对于对青霉素过敏的患者，克林霉素将是津巴布韦治疗和/或化学预防使用的首选药物。
