Zilişteanu E, Creţescu L
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1975 Jul-Sep;20(3):137-46.
Immunity in influenza is a complex phenomenon that depends upon numerous factors whose importance is not yet sufficiently known. The following mechanisms of defence are triggered by infection with the influenza virus: (a) The immune secretory system: -- IgA antibodies, --immune response in terms of the vaccinating dose, previous immunologic experience and time (appraised according to the moment in which infection started). (b) Serum antibodies: -- to the soluble antigen, -- to surface particulate antigens (hemagglutinin and neuraminidase), --antihemagglutinin and antineuraminidase antibodies, indicating the degree of protection. (c) Cellular immunity: -- influenza virus inducing the proliferation of lymphocytes in vitro and activating the inhibitory factor of mononuclear migration, -- mediated immunity. These problems of immunity have not yet been fully elucidated.
流感免疫是一种复杂现象,它取决于众多因素,而这些因素的重要性尚未得到充分了解。流感病毒感染会引发以下防御机制:(a) 免疫分泌系统:——IgA抗体,——根据接种剂量、既往免疫经验和时间(根据感染开始时间评估)的免疫反应。(b) 血清抗体:——针对可溶性抗原,——针对表面颗粒抗原(血凝素和神经氨酸酶),——抗血凝素和抗神经氨酸酶抗体,表明保护程度。(c) 细胞免疫:——流感病毒在体外诱导淋巴细胞增殖并激活单核细胞迁移抑制因子,——介导免疫。这些免疫问题尚未完全阐明。