Husain M, Jha D, Vatsal D K, Thaman D, Gupta A, Husain N, Gupta R K
Department of Neurosurgery, King George's Medical College, Lucknow, India.
Acta Neurochir (Wien). 2003 May;145(5):369-75; discussion 375-6. doi: 10.1007/s00701-003-0033-2.
Neuro-endoscopic surgery is finding increasing application for various clinical conditions. We present our experience of 100 cases of diverse intracranial lesions, including infections, managed by neuro-endoscopy in a busy neurosurgical department in the developing world.
One hundred patients treated from March 1996 to February 2002 formed the study group. Management of hydrocephalous by Endoscopic third ventriculostomy (ETV) was the aim in 75 patients with or without diagnostic biopsy. Excision or resection was attempted in 25 patients with juxtaventricular or intraventricular lesions. Endoscopic procedures included total tumour resection, partial resection, biopsy, stent placement, Monroplasty, septostomy and third ventriculostomy. Outcomes of endoscopic surgery were evaluated with respect to clinical and/or radiological improvement, complications and need for additional therapy.
Endoscopy was the only surgical treatment in 59 patients. Intermittent lumbar drainage for cerebrospinal fluid leak, shunt, microsurgery and/or repeat endoscopic surgery were additional treatments needed in 39 patients, who subsequently had increased hospital stay, postoperative morbidity and a higher cost of treatment. Peroperative bleeding due to distorted anatomy and obscured vision in 2 patients with post-infective loculated hydrocephalus (LH) resulted in two fatalities (2%) in the early post-operative period.
Neuro-endoscopic surgery cuts down operative time and hospital stay, reduces cost and results in a faster turnover of the patients. It is a versatile and useful tool for a busy neurosurgical department.
神经内镜手术在各种临床病症中的应用越来越广泛。我们介绍了在发展中国家一个繁忙的神经外科科室,应用神经内镜治疗100例包括感染在内的各种颅内病变的经验。
1996年3月至2002年2月治疗的100例患者组成研究组。75例有或无诊断性活检的脑积水患者,目标是通过内镜下第三脑室造瘘术(ETV)进行治疗。25例室旁或脑室内病变患者尝试进行切除或部分切除。内镜手术包括肿瘤全切除、部分切除、活检、支架置入、Monro孔成形术、造瘘术和第三脑室造瘘术。根据临床和/或影像学改善情况、并发症以及是否需要额外治疗来评估内镜手术的结果。
59例患者内镜手术是唯一的手术治疗方式。39例患者还需要进行脑脊液漏的间歇性腰大池引流、分流术、显微手术和/或重复内镜手术,这些患者随后住院时间延长、术后发病率增加且治疗费用更高。2例感染后局限性脑积水(LH)患者因解剖结构扭曲和视野不清导致术中出血,术后早期出现2例死亡(2%)。
神经内镜手术缩短了手术时间和住院时间,降低了成本,使患者周转更快。对于繁忙的神经外科科室来说,它是一种多功能且有用的工具。