小鼠食管中的骨骼肌生成并非通过转分化发生。
Skeletal myogenesis in the mouse esophagus does not occur through transdifferentiation.
作者信息
Rishniw Mark, Xin Hong-Bo, Deng Ke-Yu, Kotlikoff Michael I
出版信息
Genesis. 2003 Jun;36(2):81-2. doi: 10.1002/gene.10198.
PMID:12820168
Abstract
To determine the developmental history of murine esophageal skeletal muscle, smooth muscle cells were fate mapped by lineage-specific recombination and phenotypically marked by eGFP. Examination of embryonic and postnatal tissues revealed that esophageal skeletal muscle does not arise from transdifferentiation of committed smooth muscle cells.
摘要
为了确定小鼠食管骨骼肌的发育史，通过谱系特异性重组对平滑肌细胞进行命运图谱分析，并用增强绿色荧光蛋白（eGFP）进行表型标记。对胚胎和出生后组织的检查表明，食管骨骼肌并非源自定向平滑肌细胞的转分化。
Zotero 插件