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小鼠食管中的骨骼肌生成并非通过转分化发生。

Skeletal myogenesis in the mouse esophagus does not occur through transdifferentiation.

作者信息

Rishniw Mark, Xin Hong-Bo, Deng Ke-Yu, Kotlikoff Michael I

出版信息

Genesis. 2003 Jun;36(2):81-2. doi: 10.1002/gene.10198.

DOI:10.1002/gene.10198
PMID:12820168
Abstract

To determine the developmental history of murine esophageal skeletal muscle, smooth muscle cells were fate mapped by lineage-specific recombination and phenotypically marked by eGFP. Examination of embryonic and postnatal tissues revealed that esophageal skeletal muscle does not arise from transdifferentiation of committed smooth muscle cells.

摘要

为了确定小鼠食管骨骼肌的发育史，通过谱系特异性重组对平滑肌细胞进行命运图谱分析，并用增强绿色荧光蛋白（eGFP）进行表型标记。对胚胎和出生后组织的检查表明，食管骨骼肌并非源自定向平滑肌细胞的转分化。

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Skeletal myogenesis in the mouse esophagus does not occur through transdifferentiation.小鼠食管中的骨骼肌生成并非通过转分化发生。
Genesis. 2003 Jun;36(2):81-2. doi: 10.1002/gene.10198.
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Evidence for developmentally programmed transdifferentiation in mouse esophageal muscle.小鼠食管肌肉中发育编程性转分化的证据。
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The expression of nestin delineates skeletal muscle differentiation in the developing rat esophagus.巢蛋白的表达描绘了发育中的大鼠食管中的骨骼肌分化。
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