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阿加曲班抗凝治疗成功治愈1例肝素诱导的血小板减少伴血栓形成综合征患者经皮冠状动脉介入治疗期间的顽固性血栓形成

Obstinate thrombosis during percutaneous coronary intervention in a case with heparin-induced thrombocytopenia with thrombosis syndrome successfully treated by argatroban anticoagulant therapy.

作者信息

Sakai Katsuyuki, Oda Hirotaka, Honsako Akihiro, Takahashi Kazuyoshi, Miida Tutomu, Higuma Norio

机构信息

Department of Cardiology, Niigata City General Hospital, Niigata, Japan.

出版信息

Catheter Cardiovasc Interv. 2003 Jul;59(3):351-4. doi: 10.1002/ccd.10536.

DOI:10.1002/ccd.10536
PMID:12822157
Abstract

We describe a case of massive coronary thrombus after the coronary stenting due to heparin-induced thrombocytopenia with thrombosis syndrome (HITTS). Only argatroban was able to resolve the thrombus. This is the first case in which argatroban successfully treated massive thrombus during percutaneous coronary intervention in a patient with HITTS.

摘要

我们描述了一例因肝素诱导的血小板减少伴血栓形成综合征（HITTS）导致冠状动脉支架置入术后出现大量冠状动脉血栓的病例。仅阿加曲班能够溶解血栓。这是首例阿加曲班成功治疗HITTS患者经皮冠状动脉介入治疗期间大量血栓的病例。

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引用本文的文献

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Coronary thrombosis due to heparin-induced thrombocytopenia after percutaneous coronary intervention: Easy to miss, uneasy to prevent.经皮冠状动脉介入治疗后肝素诱导的血小板减少症导致的冠状动脉血栓形成：易漏诊，难预防。
Clin Case Rep. 2020 Nov 7;9(1):90-92. doi: 10.1002/ccr3.3448. eCollection 2021 Jan.
2
The Pharmacotherapy of Heparin-Induced Thrombocytopenia (HIT) : A Review of Contemporary Therapeutic Challenges in Clinical Practice.肝素诱导的血小板减少症（HIT）的药物治疗：临床实践中当代治疗挑战的综述
Malays J Med Sci. 2008 Apr;15(2):3-13.
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Heparin-induced thrombocytopenia in a case of endovascular aneurysm coiling.
血管内动脉瘤栓塞术中的肝素诱导的血小板减少症。
AJNR Am J Neuroradiol. 2007 Jan;28(1):155-8.