Kel A E, Gössling E, Reuter I, Cheremushkin E, Kel-Margoulis O V, Wingender E
BIOBASE GmbH, Halchtersche Str. 33, D-38304 Wolfenbüttel, Germany.
Nucleic Acids Res. 2003 Jul 1;31(13):3576-9. doi: 10.1093/nar/gkg585.
Match is a weight matrix-based tool for searching putative transcription factor binding sites in DNA sequences. Match is closely interconnected and distributed together with the TRANSFAC database. In particular, Match uses the matrix library collected in TRANSFAC and therefore provides the possibility to search for a great variety of different transcription factor binding sites. Several sets of optimised matrix cut-off values are built in the system to provide a variety of search modes of different stringency. The user may construct and save his/her specific user profiles which are selected subsets of matrices including default or user-defined cut-off values. Furthermore a number of tissue-specific profiles are provided that were compiled by the TRANSFAC team. A public version of the Match tool is available at: http://www.gene-regulation.com/pub/programs.html#match. The same program with a different web interface can be found at http://compel.bionet.nsc.ru/Match/Match.html. An advanced version of the tool called Match Professional is available at http://www.biobase.de.
Match是一种基于权重矩阵的工具,用于在DNA序列中搜索假定的转录因子结合位点。Match与TRANSFAC数据库紧密相连并一起发布。特别地,Match使用TRANSFAC中收集的矩阵库,因此提供了搜索多种不同转录因子结合位点的可能性。系统内置了几组优化的矩阵截止值,以提供不同严格程度的多种搜索模式。用户可以构建并保存其特定的用户配置文件,这些文件是包括默认或用户定义截止值在内的矩阵选定子集。此外,还提供了一些由TRANSFAC团队汇编的组织特异性配置文件。Match工具的公共版本可在以下网址获取:http://www.gene-regulation.com/pub/programs.html#match 。具有不同网页界面的相同程序可在http://compel.bionet.nsc.ru/Match/Match.html找到。该工具的高级版本Match Professional可在http://www.biobase.de获取。