FootPrinter：一个专为系统发育足迹法设计的程序。
FootPrinter: A program designed for phylogenetic footprinting.
作者信息
Blanchette Mathieu, Tompa Martin
机构信息
Center for Biomolecular Science and Engineering, University of California, Santa Cruz, 1156 High St, Santa Cruz, CA 95064, USA.
出版信息
Nucleic Acids Res. 2003 Jul 1;31(13):3840-2. doi: 10.1093/nar/gkg606.
Abstract
Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of homologous regulatory regions, usually collected from multiple species. It does so by identifying the best conserved motifs in those homologous regions. This note describes web software that has been designed specifically for this purpose, making use of the phylogenetic relationships among the homologous sequences in order to make more accurate predictions. The software is called FootPrinter and is available at http://bio.cs.washington.edu/software.html.
摘要
系统发育足迹法是一种在一组同源调控区域中发现调控元件的方法，这些同源调控区域通常是从多个物种中收集而来的。该方法通过识别这些同源区域中最保守的基序来实现。本说明介绍了专门为此目的设计的网络软件，该软件利用同源序列之间的系统发育关系来进行更准确的预测。该软件名为FootPrinter，可从http://bio.cs.washington.edu/software.html获取。
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本文引用的文献
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Algorithms for phylogenetic footprinting.系统发育足迹分析算法。
J Comput Biol. 2002;9(2):211-23. doi: 10.1089/10665270252935421.
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Discovery of regulatory elements by a computational method for phylogenetic footprinting.通过系统发育足迹法的计算方法发现调控元件。
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