Walsh Margaret M, Hilton Joan F, Ellison James A, Gee Lauren, Chesney Margaret A, Tomar Scott L, Ernster Virginia L
Room 495, Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, 3333 California Street, San Francisco, CA 94143-1361, USA.
Addict Behav. 2003 Aug;28(6):1095-113. doi: 10.1016/s0306-4603(02)00228-9.
To determine the efficacy of a spit tobacco (ST) intervention designed to promote ST cessation and discourage ST initiation among male high school baseball athletes.
This study was a cluster-randomized controlled trial. Forty-four randomly selected high schools in rural California were randomized within strata (prevalence of ST use and number and size of baseball teams) to either the intervention or the control group. Ninety-three percent of eligible baseball athletes participated, yielding 516 subjects in 22 intervention schools and 568 subjects in 22 control schools. Prevalences of sustained ST cessation and ST use initiation over 1 year were assessed by self-report. Multivariate logistic regression models for clustered responses were used to test the null hypotheses of no association between group and the two outcomes, adjusted for the stratified design and baseline imbalances between groups in significant predictors of ST use.
Prevalence of cessation was 27% in intervention high schools and 14% in control high schools (odds ratio (OR)=2.29; 95% confidence interval (CI), 1.36-3.87). The intervention was especially effective in promoting cessation among those who, at baseline, lacked confidence that they could quit (OR=6.4; 95% CI, 1.0-4.3), among freshmen (OR=15; 95% CI, 0.9-260), and among nonsmokers (OR=3.2; 95% CI, 0.9-11). There was no significant difference between groups in the prevalence of ST initiation.
This intervention was effective in promoting ST cessation, but was ineffective in preventing initiation of ST use by nonusers.
确定一项旨在促进男性高中棒球运动员戒烟并阻止其开始使用含烟草咀嚼物(ST)的干预措施的效果。
本研究为整群随机对照试验。在加利福尼亚农村地区随机选取的44所高中,按分层(ST使用流行率以及棒球队数量和规模)随机分为干预组或对照组。符合条件的棒球运动员中有93%参与,干预组22所学校中有516名受试者,对照组22所学校中有568名受试者。通过自我报告评估1年内持续戒烟和开始使用ST的流行率。使用多变量逻辑回归模型对聚类反应进行分析,以检验组与两个结果之间无关联的零假设,并针对分层设计以及组间在ST使用的重要预测因素方面的基线不平衡进行了调整。
干预组高中的戒烟率为27%,对照组高中为14%(优势比(OR)=2.29;95%置信区间(CI),1.36 - 3.87)。该干预措施在促进基线时对能否戒烟缺乏信心者(OR = 6.4;95% CI,1.0 - 4.3)、新生(OR = 15;95% CI,0.9 - 260)以及非吸烟者(OR = 3.2;95% CI,0.9 - 11)戒烟方面特别有效。两组在开始使用ST的流行率上无显著差异。
该干预措施在促进ST戒烟方面有效,但在防止非使用者开始使用ST方面无效。